Nemska V.Yaneva S.Georgieva N.Danalev D.2024-07-162024-07-162024-07-162024-07-162023-01-011314-79781314-7471SCOPUS_ID:85152133226https://rlib.uctm.edu/handle/123456789/1420Nowadays, mushrooms are widely studied due to the various bioactive substances they produce. They define their antibacterial, antifungal, antioxidant, antitumor, cytostatic and anti-inflammatory properties which are beneficial for human health. This study aimed to determine the antimicrobial activity of different (hot and cold ethanol/ dichloromethane/ hexane) extracts from the fungus species Lepista personata against two test microorganisms: Escherichia coli NBIMCC K12 407 and Bacillus subtilis NBIMCC 3562. The antimicrobial assays were performed applying the classical disc diffusion method. The sensitivity of test microorganisms was determined according to the zone of inhibition which appeared around the discs after 24 h of incubation at 30°C - 37°C. All extracts were dissolved in 200 mM dimethyl sulfoxide, which was used as a control sample. Results showed that E. coli NBIMCC K12 407 is susceptible to dimethyl sulfoxide whereas B. subtilis NBIMCC 3562 showed no growth inhibition. All mushroom extracts also showed no inhibitory activity against B. subtilis NBIMCC 3562. At the same time, only the dichloromethane extract obtained after hot extraction inhibited the growth of E. coli NBIMCC K12 407.enArticle