Marinova P.Marinov M.Georgiev D.Becheva M.Penchev P.Stoyanov N.2024-07-102024-07-102024-07-102024-07-102019-01-010035-393010.33224/rrch/2019.64.7.06SCOPUS_ID:85072621270https://rlib.uctm.edu/handle/123456789/547The present work presents a synthesis, characterization and antimicrobial activitiy of new Pt(IV) and Ru(III) complexes of (9’-fluorene)-spiro-5-hydantoin (HL1) and (9’-fluorene)-spiro-5-(2-thiohydantoin) (HL2). The complexes were investigated by elemental analysis, UV-Vis and IR spectroscopy. The free ligands were studied by UV-Vis, IR, 1H NMR, 13C NMR and Raman spectroscopy. The antimicrobial tests of HL1 showed week bacteriostatic effect against Staphylococcus aureus ATCC 6538. The results for [Pt(L1)2(H2O)2(OH-)2] complex showed a good antimicrobial activity against Esсherichia coli ATCC 8739, Bacillus licheniformis ATCC 6633, S. aureus and the absence of such effect on the yeasts. The HL2 and its [Pt(L2)2(H2O)2(OH-)2] and [Ru(L2)3(H2O)3] complexes do not possess antimicrobial activity against the tested bacteria and yeasts.enArticle