Vladkova T.Akuzov D.Klöppel A.Brümmer F.2024-07-162024-07-162024-07-162024-07-162014-01-011314-79781314-7471SCOPUS_ID:84901669065https://rlib.uctm.edu/handle/123456789/1052Biofilm formation is the initial step ofthe complex marine biofouling process, limiting the performance ofsubmerged surfaces in numerous applications. No technology is known up to now capable to stop the marine biofilm development even on biocidal paints coated surfaces. Several non-toxic approaches for control over marine biofilms based on physi-cal, chemical or/and biological methods, most of them inspired by the nature, are currently on search. Surface patterning, enzyme alternatives of toxic biocides and nature derived anti-biofilm agents (natural biocides, bio-surfactants/dispersants and quorum sensing inhibitors) are in the scope of this review.enArticle