Lad U.Kale G.Bryaskova R.2024-07-102024-07-102024-07-102024-07-102014-01-011945-71110013-465110.1149/2.018405jesSCOPUS_ID:84904812954https://rlib.uctm.edu/handle/123456789/314The amperometric response of sarcosine was measured in aqueous media containing ferrocene monocarboxylic acid using the redox enzyme sarcosine oxidase (SOD) immobilized in a composite material based on polyvinyl alcohol (PVA) and partially prehydrolyzed tetraethyl orthosilicate (pphTEOS) at the surface of ``in-house`` fabricated graphite electrodes. For comparison, separate electrodes consisting of silver and gold nanoparticles (Ag/AuNPs) embedded in the PVA-pphTEOS matrix was prepared employing a novel sol-gel process based on the in situ chemical reduction of Ag or Au ions using PVA both, as a reducing agent and stabilizer. The analytical performance of the enzyme electrodes was studied in terms of linear ranges, sensitivities, response times, limits of detection, reproducibility and stability. © 2014 The Electrochemical Society. All rights reserved.enArticle