SILVER NANOPARTICLES INCORPORATED INTO POROUS COLLAGEN SCAFFOLDS
No Thumbnail Available
Date
2022-01-01
External link to pdf file
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85139992511&origin=inward
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In this work, we present a simple, rapid and cost-effective microwave-assisted method for silver nanoparticles synthesis by chemical reduction using an aqueous solution of silver nitrate, ethanol and ammonia. The effect of reagent concentrations and the heating time was investigated. Samples were analyzed through UV-Vis spectroscopy and transmission electron microscopy. Furthermore, the obtained silver nanoparticles were mixed with collagen dispersions to prepare porous scaffolds by vacuum-sublimation drying. Silver nanoparticles can adhere to the bacterial cell wall subsequently causing its death. The microbiological study showed that the collagen scaffolds with incorporated silver nanoparticles exhibited antibacterial activity against Bacillus subtilis NBIMCC 3562 and Escherichia coli NBIMCC 407 bacteria and could find potential applications in medicine.