The effect of camphor and borneol on rat thymocyte viability and oxidative stress

Simple item page
creativework.keywordsBorneol, Camphor, Cytotoxicity, Mitochondrial membrane Potential, Oxidative stress
dc.contributor.authorCherneva E.
dc.contributor.authorPavlovic V.
dc.contributor.authorSmelcerovic A.
dc.contributor.authorYancheva D.
dc.date.accessioned2024-07-10T14:27:03Z
dc.date.accessioned2024-07-10T14:47:58Z
dc.date.available2024-07-10T14:27:03Z
dc.date.available2024-07-10T14:47:58Z
dc.date.issued2012-09-01
dc.description.abstractCamphor and borneol are wildly distributed in the essential oils of medicinal plants from various parts of the World. Our study has been carried out to evaluate the effect of these two bicyclic monoterpenes on rat thymocytes. Camphor and borneol at concentrations of 0.5 and 5 μg/mL did not induce significant toxicity on the immune system cells, while a significant increase of thymocyte viability was detected when cells were incubated with 50 μg/mL of camphor. A significant increase of cell viability was similarly detected when thymocytes were cultivated with borneol at concentrations of 0.5 and 5 μg/mL. The role of camphor and borneol in reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) disturbances in rat thymocytes as well as their potential mechanism(s) of action were also discussed. © 2012 by the authors.
dc.identifier.doi10.3390/molecules170910258
dc.identifier.issn1420-3049
dc.identifier.scopusSCOPUS_ID:84866905734en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/254
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866905734&origin=inward
dc.titleThe effect of camphor and borneol on rat thymocyte viability and oxidative stress
dc.typeArticle
oaire.citation.issue9
oaire.citation.volume17
Files
Collections
Articles