Synthesis and antimicrobial study of new Pt(IV) and Ru(III) complexes of fluorenylspirohydantoins

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creativework.publisherEditura Academiei Romaneen
dc.contributor.authorMarinova P.
dc.contributor.authorMarinov M.
dc.contributor.authorGeorgiev D.
dc.contributor.authorBecheva M.
dc.contributor.authorPenchev P.
dc.contributor.authorStoyanov N.
dc.date.accessioned2024-07-10T14:27:04Z
dc.date.accessioned2024-07-10T14:49:30Z
dc.date.available2024-07-10T14:27:04Z
dc.date.available2024-07-10T14:49:30Z
dc.date.issued2019-01-01
dc.description.abstractThe present work presents a synthesis, characterization and antimicrobial activitiy of new Pt(IV) and Ru(III) complexes of (9’-fluorene)-spiro-5-hydantoin (HL1) and (9’-fluorene)-spiro-5-(2-thiohydantoin) (HL2). The complexes were investigated by elemental analysis, UV-Vis and IR spectroscopy. The free ligands were studied by UV-Vis, IR, 1H NMR, 13C NMR and Raman spectroscopy. The antimicrobial tests of HL1 showed week bacteriostatic effect against Staphylococcus aureus ATCC 6538. The results for [Pt(L1)2(H2O)2(OH-)2] complex showed a good antimicrobial activity against Esсherichia coli ATCC 8739, Bacillus licheniformis ATCC 6633, S. aureus and the absence of such effect on the yeasts. The HL2 and its [Pt(L2)2(H2O)2(OH-)2] and [Ru(L2)3(H2O)3] complexes do not possess antimicrobial activity against the tested bacteria and yeasts.
dc.identifier.doi10.33224/rrch/2019.64.7.06
dc.identifier.issn0035-3930
dc.identifier.scopusSCOPUS_ID:85072621270en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/547
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85072621270&origin=inward
dc.titleSynthesis and antimicrobial study of new Pt(IV) and Ru(III) complexes of fluorenylspirohydantoins
dc.typeArticle
oaire.citation.issue7
oaire.citation.volume64
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