Organic/inorganic bioactive materials part I: Synthesis, structure and in vitro assessment of collagen/silicocarnotite biocoatings

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creativework.keywordsBiocoatings, Collagen, In vitro bioactivity, Silicocarnotite
dc.contributor.authorHristov V.
dc.contributor.authorRadev L.
dc.contributor.authorSamuneva B.
dc.contributor.authorApostolov G.
dc.date.accessioned2024-07-10T14:27:03Z
dc.date.accessioned2024-07-10T14:47:26Z
dc.date.available2024-07-10T14:27:03Z
dc.date.available2024-07-10T14:47:26Z
dc.date.issued2009-10-19
dc.description.abstractThe silicocarnotite, as an inorganic part of the coatings, has been synthesized using a polystep sol-gel method. The chemical composition of the prepared silicocarnotite sol is described as 58.12 CaO, 29.42 P2O5, 12.45 SiO2 (wt%), where Ca/P+Si = 1,67. The acid soluble type I collagen, as an organic part of the obtained coatings, was mixed with silicocarnotite powder in a weight ratio of 25:75 and 75:25 weight ratio without cross-linkage. The acidity of the obtained mixture was readjust with 25% NH4OH to pH = 9.0. The mixture was then dried at 37°C for 12 h. The growth of B-type carbonate containing hydroxyapatite (B-type CO3HA) in which CO32+ → PO43- on the surface of collagen/silicocarnotite coatings soaked in 1.5 simulated body fluid (1.5 SBF) was observed. The nucleation of B-type CO3HA was estimated on the obtained coatings after 3 days immersion in 1.5 SBF. The negatively charged carboxylate groups from the collagen surface may be responsible for the HA deposition. This was confirmed by the ``red shift`` of carboxylate groups of collagen molecules in the FTIR spectra. After soaking in 1.5 SBF, the morphology of prepared coatings and HA formation was observed by SEM. © Versita Warsaw and Springer-Verlag Berlin Heidelberg 2009.
dc.identifier.doi10.2478/s11532-009-0067-2
dc.identifier.issn1895-1066
dc.identifier.issn1644-3624
dc.identifier.scopusSCOPUS_ID:70349972135en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/171
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349972135&origin=inward
dc.titleOrganic/inorganic bioactive materials part I: Synthesis, structure and in vitro assessment of collagen/silicocarnotite biocoatings
dc.typeArticle
oaire.citation.issue4
oaire.citation.volume7
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