Recent Progress in Terrestrial Biota-Derived Anti-Biofilm Agents for Medical Applications

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creativework.keywordsanti-biofilm agents, biocidal and non-biocidal approaches, targeted stage, terrestrial biota
creativework.publisherMultidisciplinary Digital Publishing Institute (MDPI)en
dc.contributor.authorVladkova T.G.
dc.contributor.authorSmani Y.
dc.contributor.authorMartinov B.L.
dc.contributor.authorGospodinova D.N.
dc.date.accessioned2024-11-13T14:47:19Z
dc.date.accessioned2024-11-14T07:26:03Z
dc.date.available2024-11-13T14:47:19Z
dc.date.available2024-11-14T07:26:03Z
dc.date.issued2024-09-01
dc.description.abstractThe terrestrial biota is a rich source of biologically active substances whose anti-biofilm potential is not studied enough. The aim of this review is to outline a variety of terrestrial sources of antimicrobial agents with the ability to inhibit different stages of biofilm development, expecting to give some ideas for their utilization in improved anti-biofilm treatments. It provides an update for the last 5 years on anti-biofilm plant products and derivatives, essential oils, antimicrobial peptides, biosurfactants, etc., that are promising candidates for providing novel alternative approaches to combating multidrug-resistant biofilm-associated infections. Based on the reduction in bacterial adhesion to material and cell surfaces, the anti-adhesion strategy appears interesting for the prevention of bacterial attachment in combating a broad range of mono- and multispecies bacterial biofilms. So far, few studies have been carried out in this direction. Anti-biofilm coatings made by or containing biologically active products from terrestrial biota have scarcely been studied although they are of significant interest for a reduction in infections associated with medical devices. Combination therapy with commercial antibiotics and natural products is accepted now as a promising base for future advances in anti-biofilm treatment. In vivo testing and clinical trials are necessary for clinical application.
dc.identifier.doi10.3390/applmicrobiol4030094
dc.identifier.issn2673-8007
dc.identifier.scopusSCOPUS_ID:85205115077en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/1520
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85205115077&origin=inward
dc.titleRecent Progress in Terrestrial Biota-Derived Anti-Biofilm Agents for Medical Applications
dc.typeReview
oaire.citation.issue3
oaire.citation.volume4
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