Controlled synthesis of AB2 amphiphilic triarm star-shaped block copolymers by ring-opening polymerization

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creativework.keywordsAliphatic polyesters, Micelles, Poly(ethylene oxide), Star-shaped copolymers
dc.contributor.authorPetrova S.
dc.contributor.authorRiva R.
dc.contributor.authorJérôme C.
dc.contributor.authorLecomte P.
dc.contributor.authorMateva R.
dc.date.accessioned2024-07-10T14:27:03Z
dc.date.accessioned2024-07-10T14:47:26Z
dc.date.available2024-07-10T14:27:03Z
dc.date.available2024-07-10T14:47:26Z
dc.date.issued2009-12-01
dc.description.abstractThis paper describes the synthesis of a novel amphiphilic AB2 triarm star-shaped copolymer with A = non-toxic and biocompatible hydrophilic poly(ethylene oxide) (PEO) and B = biodegradable and hydrophobic poly(ε-caprolactone) (PCL). A series of AB2 triarm star-shaped copolymers with different molecular-weights for the PCL block were successfully synthesized by a three-step procedure. α-Methoxy-ω-epoxy-poly(ethylene oxide) (PEO-epoxide) was first synthesized by the nucleophilic substitution of α-methoxy-ω-hydroxy-poly(ethylene oxide) (MPEO) on epichlorohydrin. In a second step, the α-methoxy-ω,ω′-dihydroxy-poly(ethylene oxide) (PEO(OH)2) macroinitiator was prepared by the selective hydrolysis of the ω-epoxy end-group of the PEO-epoxide chain. Finally, PEO(OH)2 was used as a macroinitiator for the ring-opening polymerization (ROP) of ε-caprolactone (εCL) catalyzed by tin octoaote (Sn(Oct)2). PEO-epoxide, PEO(OH)2 and the AB2 triarm star-shaped copolymers were assessed by 1H NMR spectroscopy, size exclusion chromatography (SEC) and MALDI-TOF. The behavior of the AB2 triarm star-shaped copolymer in aqueous solution was studied by dynamic light scattering (DLS) and transmission electron microscopy (TEM). © 2009.
dc.identifier.doi10.1016/j.eurpolymj.2009.09.009
dc.identifier.issn0014-3057
dc.identifier.scopusSCOPUS_ID:70449481097en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/176
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70449481097&origin=inward
dc.titleControlled synthesis of AB2 amphiphilic triarm star-shaped block copolymers by ring-opening polymerization
dc.typeArticle
oaire.citation.issue12
oaire.citation.volume45
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