Synthesis and Antibacterial Studies of a New Au(III) Complex with 6-Methyl-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One

Simple item page
creativework.keywords6-methyl-2-thiouracil (6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one), antimicrobial activity, gold(III) complexes
creativework.publisherMultidisciplinary Digital Publishing Institute (MDPI)en
dc.contributor.authorMarinova P.
dc.contributor.authorBurdzhiev N.
dc.contributor.authorBlazheva D.
dc.contributor.authorSlavchev A.
dc.date.accessioned2024-09-02T14:58:15Z
dc.date.accessioned2024-09-02T15:15:26Z
dc.date.available2024-09-02T14:58:15Z
dc.date.available2024-09-02T15:15:26Z
dc.date.issued2024-06-01
dc.description.abstractThis article describes the synthesis of a new metal complex using 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. The compound was analyzed using several methods, including determining its melting point and employing UV-Vis, IR, ATR, 1H NMR, HSQC, and Raman spectroscopy for the free ligand. The metal complex was formed by combining aqueous solutions of metal salts with the ligand dissolved in DMSO and water, along with NaOH in a metal-to-ligand-to-base ratio of 1:4:2. The NMR signals of the ligand were assigned using 1H-1H COSY, DEPT-135, HMBC, and HMQC spectra. Furthermore, the compound’s antimicrobial activity against Gram-positive and Gram-negative bacteria, as well as yeasts, was assessed.
dc.identifier.doi10.3390/M1827
dc.identifier.issn1422-8599
dc.identifier.scopusSCOPUS_ID:85197246932en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/1462
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85197246932&origin=inward
dc.titleSynthesis and Antibacterial Studies of a New Au(III) Complex with 6-Methyl-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One
dc.typeArticle
oaire.citation.issue2
oaire.citation.volume2024
Files
Collections
Articles