PREPARATION OF GOLD LOADED MICELLES BASED ON POLY (ETHYLENE GLYCOL) - b - POLY (4-VINYL PYRIDINE) COPOLYMERS AS A TOOL FOR BIOMEDICAL APPLICATIONS
No Thumbnail Available
Date
2017-01-01
External link to pdf file
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85124277129&origin=inward
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Well-defined block copolymers based on poly (ethylene glycol) monomethyl ether and poly (4-vinyl pyridine) (PEG-b-P4VP) were prepared by atom transfer radical polymerization (ATRP). PEG-b-P4VP block copolymer self assembled in an aqueous medium with formation of nanosized spherical micelles was thus prepared. Gold nanoparticles were successfully loaded into PEG-b-P4VP based micelles. This was confirmed by UV-vis, TEM and DLS analysis. The cytotoxicity of gold loaded micelles against MDA-MB-231 breast cancer cells and L929 fibroblasts was determined.