A mathematical model of cellular immune response to leukemia

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creativework.keywordsDendritic cells, Integro-differential equations, Leukemia, Nonlinear dynamics, Vaccination
dc.contributor.authorKolev M.
dc.date.accessioned2024-12-04T13:38:24Z
dc.date.accessioned2024-12-04T13:46:56Z
dc.date.available2024-12-04T13:38:24Z
dc.date.available2024-12-04T13:46:56Z
dc.date.issued2005-05-01
dc.description.abstractThe cell-mediated immune response is a very important part of the defence mechanism against cancer. In this paper, we present a model of the cellular immune response to leukemia. The model is developed with statistical methods analogous to those of kinetic theory. The cells of the interacting populations are characterized by a microscopic functional state variable. The development of the concept of inner functional state is considered. A new possibility for definition of the activation state, suitable for experimental evaluation, for three particular cell populations is proposed. The presented simulations are related to the modelling of three types of vaccinations. © 2005 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.mcm.2005.05.003
dc.identifier.issn0895-7177
dc.identifier.scopusSCOPUS_ID:26844512863en
dc.identifier.urihttps://rlib.uctm.edu/handle/123456789/1536
dc.language.isoen
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=26844512863&origin=inward
dc.titleA mathematical model of cellular immune response to leukemia
dc.typeArticle
oaire.citation.issue10
oaire.citation.volume41
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